产品货号：
Z30969
中文名称：
Peroxiredoxin 2/PRDX2抗体
英文名称：
Anti-Peroxiredoxin 2/PRDX2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Peroxiredoxin 2/PRDX2 Antibody |
| 指标别名 | NKEF B;NKEFB;peroxiredoxin 2;PRDX2;PRP;PRX II;PRX2;PRXII;TDPX1;Thioredoxin peroxidase 1;TSA |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | PRDX2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Peroxiredoxin 2(181-198aa DTIKPNVDDSKEYFSKHN),identical to the related mouse and rat sequences. |
| 实际分子量 | 22KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PRDX2(peroxiredoxin 2) also known as NKEFB,PRP,PRX2,PRXII or TPX1,is a protein that in humans is encoded by the PRDX2 gene.This gene encodes a member of the peroxiredoxin family of antioxidant enzymes,which reduce hydrogen peroxide and alkyl hydroperoxides.The encoded protein may play an antioxidant protective role in cells,and may contribute to the antiviral activity of CD8(+) T-cells.This protein may have a proliferative effect and play a role in cancer development or progression.The Prdx2 -/- mice were healthy in appearance and fertile.Choi et al.(2005) demonstrated that PRDX2 is a negative regulator of PDGF signaling.Prx II deficiency results in increased production of peroxide,enhanced activation of PDGF receptor and phospholipase C-gamma-1,and subsequently increased cell proliferation and migration in response to PDGF.PRX2 accounted for about half of the thioredoxin activity in parasite extracts,and PRX2 expression was increased in the presence of chloroquine,regardless of P.falciparum strain susceptibility to the drug. |
| Uniprot ID | P32119 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | peroxiredoxin 2 |
| 蛋白名全称 | Peroxiredoxin-2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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